Pesquisa | Secretaria de Estado da Saúde

1.

Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5.

Kimura, Izumi; Yamasoba, Daichi; Tamura, Tomokazu; Nao, Naganori; Suzuki, Tateki; Oda, Yoshitaka; Mitoma, Shuya; Ito, Jumpei; Nasser, Hesham; Zahradnik, Jiri; Uriu, Keiya; Fujita, Shigeru; Kosugi, Yusuke; Wang, Lei; Tsuda, Masumi; Kishimoto, Mai; Ito, Hayato; Suzuki, Rigel; Shimizu, Ryo; Begum, Mst Monira; Yoshimatsu, Kumiko; Kimura, Kanako Terakado; Sasaki, Jiei; Sasaki-Tabata, Kaori; Yamamoto, Yuki; Nagamoto, Tetsuharu; Kanamune, Jun; Kobiyama, Kouji; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Shirakawa, Kotaro; Takaori-Kondo, Akifumi; Kuramochi, Jin; Schreiber, Gideon; Ishii, Ken J; Hashiguchi, Takao; Ikeda, Terumasa; Saito, Akatsuki; Fukuhara, Takasuke; Tanaka, Shinya; Matsuno, Keita; Sato, Kei.

Cell ; 185(21): 3992-4007.e16, 2022 10 13.

Artigo Inglês | MEDLINE | ID: mdl-36198317

2.

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike.

Yamasoba, Daichi; Kimura, Izumi; Nasser, Hesham; Morioka, Yuhei; Nao, Naganori; Ito, Jumpei; Uriu, Keiya; Tsuda, Masumi; Zahradnik, Jiri; Shirakawa, Kotaro; Suzuki, Rigel; Kishimoto, Mai; Kosugi, Yusuke; Kobiyama, Kouji; Hara, Teppei; Toyoda, Mako; Tanaka, Yuri L; Butlertanaka, Erika P; Shimizu, Ryo; Ito, Hayato; Wang, Lei; Oda, Yoshitaka; Orba, Yasuko; Sasaki, Michihito; Nagata, Kayoko; Yoshimatsu, Kumiko; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Kuramochi, Jin; Seki, Motoaki; Fujiki, Ryoji; Kaneda, Atsushi; Shimada, Tadanaga; Nakada, Taka-Aki; Sakao, Seiichiro; Suzuki, Takuji; Ueno, Takamasa; Takaori-Kondo, Akifumi; Ishii, Ken J; Schreiber, Gideon; Sawa, Hirofumi; Saito, Akatsuki; Irie, Takashi; Tanaka, Shinya; Matsuno, Keita; Fukuhara, Takasuke; Ikeda, Terumasa; Sato, Kei.

Cell ; 185(12): 2103-2115.e19, 2022 06 09.

Artigo Inglês | MEDLINE | ID: mdl-35568035

3.

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation.

Saito, Akatsuki; Irie, Takashi; Suzuki, Rigel; Maemura, Tadashi; Nasser, Hesham; Uriu, Keiya; Kosugi, Yusuke; Shirakawa, Kotaro; Sadamasu, Kenji; Kimura, Izumi; Ito, Jumpei; Wu, Jiaqi; Iwatsuki-Horimoto, Kiyoko; Ito, Mutsumi; Yamayoshi, Seiya; Loeber, Samantha; Tsuda, Masumi; Wang, Lei; Ozono, Seiya; Butlertanaka, Erika P; Tanaka, Yuri L; Shimizu, Ryo; Shimizu, Kenta; Yoshimatsu, Kumiko; Kawabata, Ryoko; Sakaguchi, Takemasa; Tokunaga, Kenzo; Yoshida, Isao; Asakura, Hiroyuki; Nagashima, Mami; Kazuma, Yasuhiro; Nomura, Ryosuke; Horisawa, Yoshihito; Yoshimura, Kazuhisa; Takaori-Kondo, Akifumi; Imai, Masaki; Tanaka, Shinya; Nakagawa, So; Ikeda, Terumasa; Fukuhara, Takasuke; Kawaoka, Yoshihiro; Sato, Kei.

Nature ; 602(7896): 300-306, 2022 02.

Artigo Inglês | MEDLINE | ID: mdl-34823256

4.

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity.

Meng, Bo; Abdullahi, Adam; Ferreira, Isabella A T M; Goonawardane, Niluka; Saito, Akatsuki; Kimura, Izumi; Yamasoba, Daichi; Gerber, Pehuén Pereyra; Fatihi, Saman; Rathore, Surabhi; Zepeda, Samantha K; Papa, Guido; Kemp, Steven A; Ikeda, Terumasa; Toyoda, Mako; Tan, Toong Seng; Kuramochi, Jin; Mitsunaga, Shigeki; Ueno, Takamasa; Shirakawa, Kotaro; Takaori-Kondo, Akifumi; Brevini, Teresa; Mallery, Donna L; Charles, Oscar J; Bowen, John E; Joshi, Anshu; Walls, Alexandra C; Jackson, Laurelle; Martin, Darren; Smith, Kenneth G C; Bradley, John; Briggs, John A G; Choi, Jinwook; Madissoon, Elo; Meyer, Kerstin B; Mlcochova, Petra; Ceron-Gutierrez, Lourdes; Doffinger, Rainer; Teichmann, Sarah A; Fisher, Andrew J; Pizzuto, Matteo S; de Marco, Anna; Corti, Davide; Hosmillo, Myra; Lee, Joo Hyeon; James, Leo C; Thukral, Lipi; Veesler, David; Sigal, Alex; Sampaziotis, Fotios.

Nature ; 603(7902): 706-714, 2022 03.

Artigo Inglês | MEDLINE | ID: mdl-35104837

5.

Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia.

Aoki, Kazunari; Hyuga, Mizuki; Tarumoto, Yusuke; Nishibuchi, Gohei; Ueda, Atsushi; Ochi, Yotaro; Sugino, Seiichi; Mikami, Takashi; Kobushi, Hirokazu; Kato, Itaru; Akahane, Koshi; Inukai, Takeshi; Takaori-Kondo, Akifumi; Takita, Junko; Ogawa, Seishi; Yusa, Kosuke.

Blood ; 143(7): 604-618, 2024 Feb 15.

Artigo Inglês | MEDLINE | ID: mdl-37922452

6.

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms.

Makishima, Hideki; Saiki, Ryunosuke; Nannya, Yasuhito; Korotev, Sophia; Gurnari, Carmelo; Takeda, June; Momozawa, Yukihide; Best, Steve; Krishnamurthy, Pramila; Yoshizato, Tetsuichi; Atsuta, Yoshiko; Shiozawa, Yusuke; Iijima-Yamashita, Yuka; Yoshida, Kenichi; Shiraishi, Yuichi; Nagata, Yasunobu; Kakiuchi, Nobuyuki; Onizuka, Makoto; Chiba, Kenichi; Tanaka, Hiroko; Kon, Ayana; Ochi, Yotaro; Nakagawa, Masahiro M; Okuda, Rurika; Mori, Takuto; Yoda, Akinori; Itonaga, Hidehiro; Miyazaki, Yasushi; Sanada, Masashi; Ishikawa, Takayuki; Chiba, Shigeru; Tsurumi, Hisashi; Kasahara, Senji; Müller-Tidow, Carsten; Takaori-Kondo, Akifumi; Ohyashiki, Kazuma; Kiguchi, Toru; Matsuda, Fumihiko; Jansen, Joop H; Polprasert, Chantana; Blombery, Piers; Kamatani, Yoichiro; Miyano, Satoru; Malcovati, Luca; Haferlach, Torsten; Kubo, Michiaki; Cazzola, Mario; Kulasekararaj, Austin G; Godley, Lucy A; Maciejewski, Jaroslaw P.

Blood ; 141(5): 534-549, 2023 02 02.

Artigo Inglês | MEDLINE | ID: mdl-36322930

7.

RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination.

Inano, Shojiro; Sato, Koichi; Katsuki, Yoko; Kobayashi, Wataru; Tanaka, Hiroki; Nakajima, Kazuhiro; Nakada, Shinichiro; Miyoshi, Hiroyuki; Knies, Kerstin; Takaori-Kondo, Akifumi; Schindler, Detlev; Ishiai, Masamichi; Kurumizaka, Hitoshi; Takata, Minoru.

Mol Cell ; 66(5): 622-634.e8, 2017 Jun 01.

Artigo Inglês | MEDLINE | ID: mdl-28575658

8.

Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the proteolysis pathway.

Kamba, Keisuke; Wan, Li; Unzai, Satoru; Morishita, Ryo; Takaori-Kondo, Akifumi; Nagata, Takashi; Katahira, Masato.

Biophys J ; 123(3): 294-306, 2024 Feb 06.

Artigo Inglês | MEDLINE | ID: mdl-38115583

9.

Clinical impact and characteristics of erythroid dysplasia in adult aplastic anaemia: Results from a multicentre registry.

Maeda, Tomoya; Matsuda, Akira; Kanda, Junya; Kawabata, Hiroshi; Ishikawa, Takayuki; Tohyama, Kaoru; Kitanaka, Akira; Araseki, Kayano; Shimbo, Kei; Hata, Tomoko; Suzuki, Takahiro; Kayano, Hidekazu; Usuki, Kensuke; Shindo-Ueda, Maki; Arima, Nobuyoshi; Nohgawa, Masaharu; Ohta, Akiko; Chiba, Shigeru; Miyazaki, Yasushi; Nakao, Shinji; Ozawa, Keiya; Arai, Shunya; Kurokawa, Mineo; Takaori-Kondo, Akifumi; Mitani, Kinuko.

Br J Haematol ; 2024 Jan 31.

Artigo Inglês | MEDLINE | ID: mdl-38296352

10.

Nardilysin determines hematopoietic stem cell fitness by regulating protein synthesis.

Oshima, Shinichiro; Sinha, Rahul; Ohno, Mikiko; Nishi, Kiyoto; Eto, Koji; Takaori-Kondo, Akifumi; Nishi, Eiichiro; Yamamoto, Ryo.

Biochem Biophys Res Commun ; 693: 149355, 2024 Jan 22.

Artigo Inglês | MEDLINE | ID: mdl-38096617

11.

Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.

Kimura, Izumi; Yamasoba, Daichi; Nasser, Hesham; Ito, Hayato; Zahradnik, Jiri; Wu, Jiaqi; Fujita, Shigeru; Uriu, Keiya; Sasaki, Jiei; Tamura, Tomokazu; Suzuki, Rigel; Deguchi, Sayaka; Plianchaisuk, Arnon; Yoshimatsu, Kumiko; Kazuma, Yasuhiro; Mitoma, Shuya; Schreiber, Gideon; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Takaori-Kondo, Akifumi; Ito, Jumpei; Shirakawa, Kotaro; Takayama, Kazuo; Irie, Takashi; Hashiguchi, Takao; Nakagawa, So; Fukuhara, Takasuke; Saito, Akatsuki; Ikeda, Terumasa; Sato, Kei.

J Virol ; 97(10): e0101123, 2023 10 31.

Artigo Inglês | MEDLINE | ID: mdl-37796123

12.

Tracing the evolutionary history of blood cells to the unicellular ancestor of animals.

Nagahata, Yosuke; Masuda, Kyoko; Nishimura, Yuji; Ikawa, Tomokatsu; Kawaoka, Shinpei; Kitawaki, Toshio; Nannya, Yasuhito; Ogawa, Seishi; Suga, Hiroshi; Satou, Yutaka; Takaori-Kondo, Akifumi; Kawamoto, Hiroshi.

Blood ; 140(24): 2611-2625, 2022 12 15.

Artigo Inglês | MEDLINE | ID: mdl-36112959

13.

Whole-genome landscape of adult T-cell leukemia/lymphoma.

Kogure, Yasunori; Kameda, Takuro; Koya, Junji; Yoshimitsu, Makoto; Nosaka, Kisato; Yasunaga, Jun-Ichirou; Imaizumi, Yoshitaka; Watanabe, Mizuki; Saito, Yuki; Ito, Yuta; McClure, Marni B; Tabata, Mariko; Shingaki, Sumito; Yoshifuji, Kota; Chiba, Kenichi; Okada, Ai; Kakiuchi, Nobuyuki; Nannya, Yasuhito; Kamiunten, Ayako; Tahira, Yuki; Akizuki, Keiichi; Sekine, Masaaki; Shide, Kotaro; Hidaka, Tomonori; Kubuki, Yoko; Kitanaka, Akira; Hidaka, Michihiro; Nakano, Nobuaki; Utsunomiya, Atae; Sica, R Alejandro; Acuna-Villaorduna, Ana; Janakiram, Murali; Shah, Urvi; Ramos, Juan Carlos; Shibata, Tatsuhiro; Takeuchi, Kengo; Takaori-Kondo, Akifumi; Miyazaki, Yasushi; Matsuoka, Masao; Ishitsuka, Kenji; Shiraishi, Yuichi; Miyano, Satoru; Ogawa, Seishi; Ye, B Hilda; Shimoda, Kazuya; Kataoka, Keisuke.

Blood ; 139(7): 967-982, 2022 02 17.

Artigo Inglês | MEDLINE | ID: mdl-34695199

14.

Efficacy of elotuzumab for multiple myeloma deteriorates after daratumumab: a multicenter retrospective study.

Nakamura, Naokazu; Arima, Nobuyoshi; Takakuwa, Teruhito; Yoshioka, Satoshi; Imada, Kazunori; Fukushima, Kentaro; Hotta, Masaaki; Fuchida, Shin-Ichi; Kanda, Junya; Uoshima, Nobuhiko; Shimura, Yuji; Tanaka, Hirokazu; Ohta, Kensuke; Kosugi, Satoru; Yagi, Hideo; Yoshihara, Satoshi; Yamamura, Ryosuke; Adachi, Yoko; Hanamoto, Hitoshi; Shibayama, Hirohiko; Hosen, Naoki; Ito, Tomoki; Shimazaki, Chihiro; Takaori-Kondo, Akifumi; Kuroda, Junya; Matsumura, Itaru; Hino, Masayuki.

Ann Hematol ; 2024 Mar 16.

Artigo Inglês | MEDLINE | ID: mdl-38492020

15.

Population Pharmacokinetic Modeling of Posaconazole in Japanese Patients Receiving Fungal Prophylaxis.

Sugimoto, Mitsuhiro; Yonezawa, Atsushi; Kanda, Junya; Itohara, Kotaro; Hira, Daiki; Yamagiwa, Takeo; Taniguchi, Risa; Hanyu, Yuta; Watanabe, Mizuki; Arai, Yasuyuki; Mizumoto, Chisaki; Kitawaki, Toshio; Kondo, Tadakazu; Yamashita, Kouhei; Takaori-Kondo, Akifumi; Terada, Tomohiro.

Ther Drug Monit ; 2024 Apr 04.

Artigo Inglês | MEDLINE | ID: mdl-38648638

16.

[Severe consciousness disturbance after cord blood transplantation for relapsed T lymphoblastic lymphoma].

Nakamura, Naokazu; Mizumoto, Chisaki; Sugimoto, Akihiko; Fujimoto, Masakazu; Ayaki, Takashi; Takaori-Kondo, Akifumi.

Rinsho Ketsueki ; 65(1): 47-51, 2024.

Artigo Japonês | MEDLINE | ID: mdl-38311389

17.

HTLV-1 bZIP factor impairs DNA mismatch repair system.

Sakurada-Aono, Maki; Sakamoto, Takashi; Kobayashi, Masayuki; Takiuchi, Yoko; Iwai, Fumie; Tada, Kohei; Sasanuma, Hiroyuki; Hirabayashi, Shigeki; Murakawa, Yasuhiro; Shirakawa, Kotaro; Sakamoto, Chihiro; Shindo, Keisuke; Yasunaga, Jun-Ichirou; Matsuoka, Masao; Pommier, Yves; Takeda, Shunichi; Takaori-Kondo, Akifumi.

Biochem Biophys Res Commun ; 657: 43-49, 2023 05 21.

Artigo Inglês | MEDLINE | ID: mdl-36972660

18.

Pretreatment blast-to-lymphocyte ratio as a prognostic marker for CD19/CD3-bispecific T cell-engaging antibodies (blinatumomab) treatment against relapsed or refractory B-precursor acute lymphoblastic leukemia.

Shimazu, Yutaka; Kitawaki, Toshio; Kondo, Tadakazu; Takaori-Kondo, Akifumi.

Cancer Immunol Immunother ; 72(11): 3861-3865, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37550429

19.

Risk factors for antibody-mediated rejection in ABO blood-type incompatible and donor-specific antibody-positive liver transplantation.

Tajima, Tetsuya; Hata, Koichiro; Haga, Hironori; Kusakabe, Jiro; Kageyama, Shoichi; Yurugi, Kimiko; Hishida, Rie; Zhao, Xiangdong; Nishikori, Momoko; Nagao, Miki; Takaori-Kondo, Akifumi; Uemoto, Shinji; Hatano, Etsuro.

Liver Transpl ; 29(7): 711-723, 2023 07 01.

Artigo Inglês | MEDLINE | ID: mdl-36749821

20.

SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.

Okamoto, Yusuke; Abe, Masako; Mu, Anfeng; Tempaku, Yasuko; Rogers, Colette B; Mochizuki, Ayako L; Katsuki, Yoko; Kanemaki, Masato T; Takaori-Kondo, Akifumi; Sobeck, Alexandra; Bielinsky, Anja-Katrin; Takata, Minoru.

Blood ; 137(3): 336-348, 2021 01 21.

Artigo Inglês | MEDLINE | ID: mdl-32735670

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